1-Ethyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-2-quinolinecarboxylic acid - Names and Identifiers
Name | 1-Ethyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-2-quinolinecarboxylic acid
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Synonyms | T66 BN EVJ B2 DVQ HF IF JF [WLN] 1-Ethy-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid 1-Ethyl-6,7,8-Trifluoro-1,4-Digydro-4-Oxo-3-Quinolinecarboxylicacid 1-ETHYL-6,7,8-TRIFLUORO-1,4-DIHYDRO-4-OXO-3-QUINOLINECARBOXYLICACID 1,4-Dihydro-1-ethyl-4-oxo-6,7,8-trifluoro-3-quinolinecarboxylic acid 1-Ethyl-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid 1-Ethyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 1-Ethyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-2-quinolinecarboxylic acid 1-Ethyl-4-oxo-6,7,8-trifluoro-1,4-dihydroquinoline-3-carboxylic acid 3-quinolinecarboxylic acid, 1-ethyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-
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CAS | 75338-42-0
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EINECS | 616-213-2 |
InChI | InChI=1/C12H8F3NO3/c1-2-16-4-6(12(18)19)11(17)5-3-7(13)8(14)9(15)10(5)16/h3-4H,2H2,1H3,(H,18,19) |
1-Ethyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-2-quinolinecarboxylic acid - Physico-chemical Properties
Molecular Formula | C12H8F3NO3
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Molar Mass | 271.19 |
Density | 1.527±0.06 g/cm3(Predicted) |
Melting Point | 211-213 °C |
Boling Point | 401.7±45.0 °C(Predicted) |
Flash Point | 196.743°C |
Vapor Presure | 0mmHg at 25°C |
Appearance | White crystal |
pKa | -0?+-.0.20(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.557 |
1-Ethyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-2-quinolinecarboxylic acid - Introduction
1-Ethyl-6,7,8-trifluoro-1, is an organic compound with the chemical formula C13H9F3NO3.
Nature:
1-Ethyl-6,7,8-trifluoro-1, acid is a white solid with a special medicinal smell. It is stable at room temperature, but decomposes at high temperatures. The compound is soluble in organic solvents such as methylene chloride and dimethyl sulfoxide, and insoluble in water.
Use:
1-Ethyl-6,7,8-trifluoro-1, acid is mainly used in the field of medicine. It is an intermediate of quinolone antibiotics and can be used in the synthesis of other drugs, such as fluoroquinolones.
Preparation Method:
1-Ethyl-6,7,8-trifluoro-1, the synthesis of acid is generally carried out by chemical reaction. A common method is to react quinolinone with ethyl lithium, followed by fluorination and carboxylation to obtain the target product.
Safety Information:
1-Ethyl-6,7,8-trifluoro-1, acid should be stored in a sealed, dry environment, away from fire and oxidizing agents. Wear protective gloves and goggles during operation to avoid contact with skin and eyes. In case of careless contact, rinse with plenty of water immediately. In case of serious discomfort, seek medical treatment.
In addition, for the preparation and use of chemicals, please always refer to the relevant safety procedures and comply with relevant regulations and guidelines.
Last Update:2024-04-09 20:52:54